HPV tiếng anh là human papillomavirus. Có khoảng 200 loại HPV và nhiều trong số đó được lây truyền qua đường tình dục. Vài loại HPV chỉ ảnh hưởng đến vùng sinh dục, một vài có thể gây mụn cóc và một số khác có thể gây ung thư đe dọa tính mạng như ung thư cổ tử cung, ung thư dương vật, hậu môn, âm đạo, âm hộ và hầu họng.
HPV lây truyền như thế nào? HPV chỉ nhiễm trên những tế bào da và lây truyền qua tiếp xúc da trực tiếp. Những loại HPV nhiễm ở vùng sinh dục, hậu môn và họng thì lây truyền qua đường tiếp xúc tình dục.

Tìm hiểu thêm về bệnh phụ khoa tại đây
NHIỄM HPV LÀ GÌ?
HPV chỉ nhiễm trên những tế bào da và lây truyền qua tiếp xúc da trực tiếp. Những loại HPV nhiễm ở vùng sinh dục, hậu môn và họng thì lây truyền qua đường tiếp xúc tình dục.
Nhiễm HPV ở miệng hay xảy ra trên những đối tượng có oral sex tức là quan hệ qua đường miệng, việc tiếp xúc giữa miệng và cơ quan sinh dục vẫn có nguy cơ nhiễm HPV
BỊ NHIỄM HPV CÓ CHỮA ĐƯỢC KHÔNG?
Chưa có điều trị đặc hiệu đối với nhiễm HPV. Mụn cóc sinh dục (sùi mào gà sinh dục) nên được điều trị và có nhiều cách điều trị hiệu quả có sẵn cho cả nam và nữ. Rất quan trọng để nói với bác sĩ của bạn về bất cứ triệu chứng liên quan nào, tìm kiếm và điều trị tế bào tiền ung thư được tìm thấy là một phần của quá trình tầm soát.
CÁCH NÀO ĐỂ TRÁNH NHIỄM HPV?
Tránh nhiễm HPV một cách hoàn toàn là điều rất khó khăn- hơn 80% người có hoạt động tình dục nhiễm ít nhất một loại HPV tại một vài thời điểm nào đó trong cuộc đời. Nhưng có vài điều bạn có thể làm để giảm nguy cơ:
- Nếu bạn đủ điều kiện hoặc nếu bác sĩ của bạn nghĩ bạn có thể có lợi từ việc chích vaccine thì bạn nên chích vaccine.
- Sử dụng bao cao su có thể làm giảm (nhưng không loại trừ) nguy cơ nhiễm HPV. Tuy nhiên nên sử dụng bao cao su cho tất cả các tiếp xúc tình dục.
- Giảm số lượng bạn tình mà bạn có.
- Tầm soát ung thư cổ tử cung nếu bạn đủ điều kiện. Ngoài việc xác định tiền ung thư, tầm soát HPV đôi khi được thực hiện đồng thời.
- Thăm khám ngay nếu bạn lo lắng bạn có mụn cóc vùng sinh dục hoặc có những dấu hiệu khác của nhiễm HPV.
- Nói chuyện với đối tác của bạn về chích ngừa HPV, tầm soát và bao cao su.
CÁC CÂU HỎI THƯỜNG GẶP
Sau đây tôi xin trả lời một số câu hỏi mà mọi người thường hỏi tôi ở bệnh viện, qua các câu hỏi này, hy vọng sẽ giúp các bạn hiểu rõ hơn về HPV
Cách kiểm tra nhiễm HPV ở phụ nữ và nam giới?
Kiểm tra HPV từ mẫu được lấy từ cổ tử cung đã có sẵn đối với một số phụ nữ như là một phần của việc tầm soát ung thư cổ tử cung. Không có xét nghiệm HPV cho nam giới và hiện không có xét nghiệm máu để kiểm tra nhiễm HPV hay không.
Nếu tôi bị nhiễm HPV tôi sẽ bị ung thư?
Chỉ một số lượng nhỏ người nhiễm HPV phát triển thành ung thư cho nên việc nhiễm HPV không có nghĩa là bạn sẽ bị ung thư. Tuy nhiên, rất quan trọng để giảm nguy cơ của việc nhiễm HPV bằng chích ngừa nếu bạn đủ điều kiện chích vaccine hoặc nếu nhà cung cấp chăm sóc sức khỏe của bạn nghĩ bạn có thể có lợi ích từ nó và nên tầm soát ung thư cổ tử cung.
Bị nhiễm HPV có tiêm phòng được không?
Bạn nên xét nghiệm để biết mình nhiễm HPV type nào, nếu bạn không hoặc chưa nhiễm HPV có trong mũi tiêm ngừa bạn hoàn toàn có thể chích ngừa HPV. Tuy nhiên việc xét nghiệm HPV trước khi tiêm ngừa là không bắt buộc trừ khi bạn đang có biểu hiện cấp của nhiễm HPV như đang bị sùi mào gà sinh dục tiến triển. Nhiễm HPV thể hiện trên xét nghiệm có thể hiện tại là âm tính nhưng trong quá khứ bạn đã từng dương tính với HPV thì việc xét nghiệm sẽ trở nên vô nghĩa. Vậy nên HPV chích tốt nhất cho người chưa từng có quan hệ tình dục.
Tôi đã chích ngừa ung thư cổ tử cung thì có cần được tầm soát không?
Mặc dù vaccine làm giảm đáng kể nguy cơ mắc các bệnh ung thư liên quan đến HPV nhưng những phụ nữ đã tiêm vaccine HPV vẫn cần được tầm soát cổ tử cung.
Tôi trên 26 tuổi vậy tôi có nên chích ngừa HPV không?
Một số người trên 26 tuổi có thể có lợi từ việc chích ngừa HPV. Ở nhiều quốc gia, việc chủng ngừa HPV được chích cho phũ nữ đến 45 tuổi và điều này cũng được ủng hộ đối với nam giới một số nước.
Nếu tôi tiếp xúc với người bị sùi mào gà sinh dục thì tôi cũng sẽ bị nhiễm HPV đúng không?
Mụn cóc sinh dục chứa một số lượng lớn virus HPV có thể lây lan, là cơ hội tốt để bạn có thể nhiễm nó. Không phải tất cả mọi người nhiễm HPV đều có mụn cóc sinh dục nhưng bạn nên nói với bác sĩ về việc tầm soát hoặc chích ngừa. Nếu bạn có mụn cóc sinh dục bạn nên được điều trị. Điều trị hiệu quả mụn cóc sinh dục đều có sẵn cho cả nam và nữ
Tôi chưa bao giờ có quan hệ tình dục thì có nên tầm soát HPV không?
Nếu bạn chưa từng có tiếp xúc tình dục, nguy cơ nhiễm HPV của bạn rất thấp nên sẽ không đáng để bạn làm xét nghiệm HPV.
Tôi không bị nhiễm HPV nên sẽ không bị ung thư liên quan đến HPV?
Điều đó có nghĩa rằng nguy cơ phát triển thành ung thư của bạn trong tương lai gần rất thấp. Tuy nhiên, bạn vẫn cần được tầm soát trong tương lai tùy thuộc vào chính sách tầm soát ở vùng bạn sống. Miễn là bạn có hoạt động tình dục, bạn có nguy cơ nhiễm virus cùng với nguy cơ nhỏ của ung thư.
Thay đổi lối sống có giúp giảm nguy cơ nhiễm HPV hay không?
Có. Bạn có thể giảm nguy cơ nhiễm HPV nếu bạn tiêm vaccine khi đủ điều kiện, sử dụng bao cao su và giảm số lượng đối tác tình dục. Bạn cũng có thể giảm nguy cơ ung thư dù bạn đã bị nhiễm HPV bằng cách tầm soát nếu đủ điều kiện và không hút thuốc.
Bao cao su có thể ngăn được HPV?
Bao cao su giảm một phần nguy cơ của việc lây nhiễm bởi vì chúng chỉ bảo vệ phần da của đường sinh dục. Càng sử dụng bao cao su thường xuyên càng tăng sự bảo vệ. Sử dụng bao cao su 100% thời gian giảm nguy cơ lây lan HPV khoảng 70%. Ít sử dụng thường xuyên nghĩa là ít được bảo vệ.
HPV gây ung thư như thế nào?
Khi bị nhiễm, cơ thể có thể loại bỏ HPV hay không. Nếu cơ thể thất bại với việc loại bỏ HPV, sự tồn tại lâu dài có thể dẫn đến những thay đổi tiền ung thư. Nếu để đó và không điều trị, một vài thay đổi này có thể tiến triền cùng với thời gian thành ung thư. Tầm soát và điều trị tiền ung thư làm giảm đáng kể nguy cơ phát triển thành ung thư.
Nếu tôi có HPV khi mang thai, nó có lây cho con tôi không?
HPV không dễ lây từ mẹ sang trẻ sơ sinh. Một số trường hợp hiếm, trẻ sinh ra từ những người mẹ có mụn cóc sinh dục do HPV 6 và 11 lúc chuyển dạ có thể bị nhiễm virus trong khi trẻ đi qua đường sinh sản. Trẻ sau đó có thể phát triển mụn cóc ở thực quản và cần điều trị phẫu thuật. Những phụ nữ đã tiêm ngừa vaccine chống HPV 6 và 11 giảm đáng kể nguy cơ mẹ truyền virus sang con.
Đối tác của tôi bảo rằng anh ấy bị nhiễm HPV. Như vậy là tôi cũng bị nhiễm?
Không nhất thiết, nhưng nhiễm HPV có thể ảnh hưởng cả 2 đối tác trong vòng vài tháng. HPV phần lớn không thể nhìn thấy nhưng nếu có những triệu chứng của HPV như mụn cóc sinh dục, bạn nên nói với bác sĩ của bạn. Bởi vì bạn hoặc đối tác của bạn có thể nhiễm HPV mà không hề biết, nếu bạn là phụ nữ có hoạt động tình dục, đáng để bạn thực hiện tầm soát ung thư cổ tử cung sẵn có. Trong một vài trường hợp, tầm soát định kỳ bao gồm xét nghiệm HPV ở cổ tử cung. Chưa có điều trị đặc hiệu với nhiễm HPV nhưng rất quan trọng để tìm kiếm và điều trị những tế bào tiền ung thư như một phần của quá trình tầm soát. Nói chuyện với nhà cung cấp sức khỏe về có nên chích ngừa HPV hay không là quyền của bạn. Không có xét nghiệm HPV chuẩn hoặc tầm soát dành cho nam giới.
Tôi đang uống thuốc ngừa thai, liệu có làm tăng nguy cơ HPV không?
Sử dụng dài hạn thuốc ngừa thai đường uống đã được tìm thấy tăng nhẹ nguy cơ ung thư cổ tử cung, nhưng chỉ trong số những phụ nữ đã bị nhiễm HPV. Hầu hết những bằng chứng của điều này đến từ những nghiên cứu trước kia và hiện tại thuốc ngừa thai với nồng độ estrogen thấp đã có sẵn. Vì vậy nguy cơ, nếu có, không rõ ràng vào thời điểm này. Có HPV là yếu tố nguy cơ chính đối với ung thư cổ tử cung và việc ngăn chặn vẫn tập trung vào việc chích ngừa để ngăn nhiễm HPV và tầm soát tiền ung thư cổ tử cung. Nếu vẫn còn mơ hồ hãy tư vấn với người cung cấp dịch vụ sức khỏe của bạn.
Vacxin HPV là gì?
Là vacxin ngừa các type HPV nguy cơ cao gây ung thư cổ tử cung và sùi mào gà sinh dục. Hiện ở Việt Nam có 2 loại vaccine HPV:
- Cervarix: nhị giá, chống lại HPV type 16, 18, chỉ sử dụng ở phụ nữ
- Gardasil: tứ giá, chống lại HPV type 6, 11, 16, 18. Hiệu quả bảo vệ của Gardasil với các tuyp HPV 16 và 18 là trên 98,2 %, hiệu quả bảo vệ mụn cóc sinh dục (sùi mào gà) lên tới 99% (HPV type 6, 11), không thấy có đề cập đến hiệu quả bảo vệ chéo lên các tuýp HPV ngừa ung thư khác ngoài 2 tuýp 16 và 18.
Tại Mỹ đã có vaccine cửu giá (Gardasil 9) được FDA cấp phép.
Tiêm vacxin HPV bao nhiêu mũi?
Phác đồ 2 mũi: 9 đến hết 14 tuổi, ngoại trừ những người bị suy giảm miễn dịch. Lịch trình tiêm: 0, 6 – 12 tháng. khoảng cách tối thiểu 5 tháng giữa 2 liều.
Phác đồ 3 mũi: 15 đến hết 26 tuổi. Lịch trình tiêm: 0, 1-2, 6 tháng. khoảng cách tối thiểu 4 tuần giữa liều 1 và 2, 12 tuần giữa liều 2 và 3, 5 tháng giữa liều 1 và 3
Tiêm 3 mũi bất kể tuổi nào trong những trường hợp suy giảm miễn dịch dịch thể hoặc qua trung gian tế bào nguyên phát hoặc thứ phát.
- Thiếu hụt kháng thể tế bào lympho B
- Khiếm khuyết từng phần hay toàn phần tế bào lympho T
- Nhiễm HIV
- Tân sinh ác tính
- Cấy ghép
- Bệnh tự miễn
- Liệu pháp ức chế miễn dịch
Có thể sử dụng phác đồ 2 mũi tiêm cho những trường hợp bắt đầu tiêm trước sinh nhật lần thứ 15 như sau:
- Hen
- Không có lách
- Đái tháo đường
- Bệnh tế bào hình liềm
- Bệnh đại thực bào mạn tính
- Bệnh mạn tính của gan, phổi, thận
- Bệnh tim
- Những khiếm khuyết rào chắn hệ thần kinh trung ương
- Thiếu hụt thành phần bổ thể tạm thời hay vĩnh viễn
Độ tuổi tốt nhất để tiêm ngừa HPV là 11 đến 12 tuổi vì:
- Đáp ứng miễn dịch tốt hơn
- Nhiều cơ hội để tiêm vaccine
- Chưa có phơi nhiễm với virus
- Miễn dịch dài hạn
- Ngăn chặn tiền ung thư gấp 2 lần
Tôi bị nhiễm HIV, tôi có thể chích ngừa HPV?
Có. Những người dương tính với HIV đáp ứng với vaccine theo cách tương tự những người không nhiễm HIV. Việc chủng ngừa cho những cá nhân suy giảm miễn dịch và dương tính với HIV được khuyến cáo đến 26 tuổi bởi vì nguy cơ gia tăng của họ đối với ung thư do HPV. Một vài cá nhân dương tính HIV có thể có lợi từ việc chích ngừa nếu đã trên 26 tuổi, bạn nên nói chuyện với người cung cấp dịch vụ sức khỏe của bạn.
Tham khảo thêm Vacxin HPV tại đây
Nếu bạn vẫn còn thắc mắc về HPV vui lòng để lại comment bên dưới hoặc chát trực tiếp với tôi nhé. 🙂
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